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Press release Communiqué de presse

May 5, 2022 5 May, 2022

Sernova to Participate in Multiple U.S. Healthcare Investor Conferences

Sernova Engages Leading U.S.-Based Healthcare Communications Firm to Broaden Awareness of Potential ‘Functional Cure’ Technology for Type 1 Diabetes

LONDON, ONTARIO – May 5, 2022 – Sernova Corp. (TSX-V:SVA) (OTCQB:SEOVF) (FSE/XETRA:PSH), a clinical stage regenerative medicine company focused on developing a potential ‘functional cure’ for type 1 diabetes (T1D) and other chronic diseases including hemophilia A and thyroid disease, today announced that the company will be participating in several upcoming U.S. healthcare industry and investor conferences. Conference details are provided below.

The Company is also pleased to announce it has engaged New York-based LifeSci Communications, a global life science and medical technologies-focused communications and marketing agency. LifeSci Communications will assist Sernova to expand and elevate its profile through strategic communications and public relations. Sernova is also working with affiliate LifeSci Advisors LLC, a leading investor relations consultancy firm serving life science companies, providing institutional investor communications and capital markets outreach services in support of the Company’s U.S. capital markets objectives.

“With multiple collaborations advancing across our pipeline and growing interest in our best-in-class cell therapy therapeutic solution platform - consisting of immune protected therapeutic cells and our proprietary Cell Pouch™ medical device - as a potential ‘functional cure’ for multiple patient populations, the timing is right to drive awareness of our unique cell therapy proposition and unprecedented clinical results including the demonstration of continuous insulin independence for over two years now in our most advanced Phase 1/2 T1D study patient, in contrast to the clinical setbacks of several of our peer companies,” commented Dr. Philip Toleikis, President & CEO of Sernova.

UPCOMING U.S. HEALTHCARE INDUSTRY AND INSTITUTIONAL INVESTOR PRESENTATIONS

Event: Roth Capital’s Canada Corporate Access Day Date: May 17, 2022 Format: Corporate presentation and 1x1 meetings with institutional investors Location: New York, NY Event: H.C. Wainwright Global Life Sciences Conference Date: May 24-25, 2022 Format: Corporate presentation and 1x1 meetings with institutional investors Location: Miami Beach, FL Event: Truist Securities Cell Therapy Symposium Date: June 28, 2022 Format: Panel expert and discussions Location: New York, NY

ABOUT SERNOVA Sernova is developing regenerative medicine cell therapeutic solutions using a medical device (Cell Pouch) and immune protected therapeutic cells / tissues (i.e. human donor cells, corrected human cells and stem cell- derived cells) to improve the treatment and quality of life of people with chronic metabolic diseases such as insulin-dependent diabetes, blood disorders including hemophilia, and other diseases treated through cellular production of proteins or hormones missing or in short supply within the body. For more information, please visit www.sernova.com. ABOUT SERNOVA’S CELL POUCH SYSTEM CELL THERAPY PLATFORM The Cell Pouch, as part of the Cell Pouch System, is a novel, proprietary, scalable, implantable macro- encapsulation device solution designed for the long-term survival and function of therapeutic cells. After implantation, the device incorporates with tissue, forming highly vascularized, native tissue chambers for the transplantation and function of therapeutic cells, that release proteins and hormones as required to treat disease. The Cell Pouch, along with therapeutic cells, has been shown to provide long-term safety and efficacy in small and large animal models of diabetes and has been proven to provide a biologically compatible environment for insulin-producing cells in humans in a Canadian first-in-human study. Sernova is currently conducting a Phase 1/2 clinical trial study at the University of Chicago. Encouraging interim results have been presented at several international scientific conferences. FOR FURTHER INFORMATION, PLEASE CONTACT: Investors and Analysts Christopher Barnes Corey Davis, Ph.D. VP, Investor Relations Managing Director Sernova Corp. LifeSci Advisors, LLC christopher.barnes@sernova.com cdavis@lifesciadvisors.com Tel: 519-902-7923 Tel: 212-915-2577 www.sernova.com Media Elizabeth Miller, M.D. LifeSci Communications emiller@lifescicomms.com FORWARD-LOOKING INFORMATION This release contains statements that, to the extent they are not recitations of historical facts, may constitute “forward-looking statements” that involve various risks, uncertainties, and assumptions, including, without limitation, statements regarding the prospects, plans, and objectives of the company. Wherever possible, but not always, words such as "expects", "plans", "anticipates", "believes", "intends", "estimates", "projects", "potential for" and similar expressions, or that events or conditions "will", "would", "may", "could" or "should" occur are used to identify forward-looking statements. These statements reflect management’s beliefs with respect to future events and are based on information currently available to management on the date such statements were made. Many factors could cause Sernova’s actual results, performances or achievements to not be as anticipated, estimated or intended or to differ materially from those expressed or implied by the forward-looking statements contained in this news release. Such factors could include, but are not limited to, the company’s ability to secure additional financing and licensing arrangements on reasonable terms, or at all; ability to conduct all required preclinical and clinical studies for the company’s Cell Pouch System and/or related technologies, including the timing and results of those trials; ability to obtain all necessary regulatory approvals, or on a timely basis; ability to in-license additional complementary technologies; ability to complete collaboration activities; ability to secure collaboration arrangements from its collaboration activities; ability to execute its business strategy and successfully compete in the market; and the inherent risks associated with the development of biotechnology combination products generally. Many of the factors are beyond our control, including those caused by, related to, or impacted by the novel coronavirus pandemic. Investors should consult the company’s quarterly and annual filings available on www.sedar.com for additional information on risks and uncertainties relating to the forward-looking statements. Sernova expressly disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.